Presentation Profile
Beyond C18: Exploring Alternative HPLC Column Chemistries for PFAS Analysis
Currently Scheduled: 10/14/2026 - 1:00 PM - 2:00 PM
Room: Exhibit Hall A4
Main Author
Cole Williams - MilliporeSigma
Abstract:
PFAS analysis commonly relies on conventional C18 HPLC columns, but alternative stationary phases may offer complementary retention and selectivity. This poster explores how expanded column selectivity options can support method development for diverse PFAS compounds. Key considerations include chromatographic retention, resolution, and mobile phase selection. By examining approaches beyond traditional C18 separations, this work provides analysts with practical guidance for selecting chromatographic parameters that improve method flexibility and separation performance.













