Presentation Profile
Beyond C18: Exploring Alternative HPLC Column Chemistries for PFAS Analysis
Main Author
Cole Williams - MilliporeSigma
Abstract:
PFAS analysis often relies on conventional C18 HPLC columns, but alternative stationary phases can provide complementary retention and selectivity. This presentation will explore how alternative stationary phase selectivities can expand method development strategies and provide additional flexibility when analyzing diverse PFAS compounds. Practical considerations for evaluating different column chemistries, including retention, resolution, and mobile phase selection, will be covered. The goal is to provide analysts with a broader perspective on selecting chromatographic parameters beyond a conventional C18 approach.
