Presentation Profile

Intermediate Level Polymer Chromatography (GPC / SEC)

Currently Scheduled: 10/16/2024 - 1:30 PM - 2:45 PM
Room: Tulip

Main Author
John Erne - Analytical Outfitters, LLC

Abstract Number: 268
Abstract:

This presentation delves into advanced detection techniques and calibration methods in Gel Permeation Chromatography (GPC), a powerful tool for analyzing polymer molecular weight distributions. Beyond the basic principles of size-exclusion chromatography, this talk explores advanced detection techniques such as static light scattering (SLS), viscometry, differential refractive index (RI), and UV-Visible (UV-Vis) detection. Each method enhances the precision of molecular weight and structural analysis, offering more insight into polymer properties.

The presentation also examines the main 3 calibration methods, including conventional calibration, universal calibration using the Mark-Houwink equation, and triple detection, which integrates RI, viscometry, and light scattering. These approaches allow for more accurate and comprehensive characterization of polymers and other macromolecules. By the end, attendees will understand how these advanced techniques improve the resolution, accuracy, and applicability of GPC in polymer science, biochemistry, and materials research.

This is the second course in a two-part series offered at GCC 2024 on polymer chromatography.  

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