Presentation Profile
Introduction to Polymer Chromatography (GPC / SEC)
Currently Scheduled: 10/16/2024 - 12:30 PM - 1:30 PM
Room: Tulip
Main Author
John Erne - Analytical Outfitters, LLC
Abstract:
Gel Permeation Chromatography (GPC), a form of size-exclusion chromatography, is used to separate and characterize molecules based on their size in solution. This presentation introduces the fundamental principles, components, and applications of GPC. It outlines the essential components of a GPC system, including the mobile phase, stationary phase, and detectors, and describes the step-by-step process involved in GPC analysis. In addition, real-world applications of GPC in fields such as polymer chemistry and biochemistry are discussed, particularly its use in determining molecular weight distributions and analyzing synthetic polymers, natural polymers and proteins.
The advantages of GPC, such as its high resolution and non-destructive nature, are weighed against its limitations, including its restriction to size-based separation. By the end of the presentation, the audience will gain a clear understanding of analytical GPC’s role in scientific research and industry.
This is the first level a two-course training series offered at GCC 2024 covering introductory and intermediate GPC.
