Presentation Profile
A practical HS-GC/MSD method translation on the quantification of Ethylene oxide and 1,4-dioxane using HydroInert Ion Source
Currently Scheduled: 10/15/2024 - 9:00 AM - 9:40 AM
Room: Floral Hall A1
Main Author
Felipe Chagas - Agilent Technologies, Inc.
- Britney Prestridge - Indorama Ventures: Indovinya
Abstract:
Countless laboratories have been impacted by the difficulty to obtain new Helium tanks and by their elevated costs. For several decades, Helium has been selected as the best carrier for gas chromatographs with mass spectrometers (GC/MSD), especially, because of its unique inertness and separation performance. Considering the helium shortage, hydrogen has been used as a carrier gas substitute, however, on conventional GC/MS ion sources, this new carrier can negatively impact the baseline noise, loose sensitivity, cause reactivity, and reduce the quality of library search matching. Agilent Technologies introduced the new HydroInert ion source, specially designed to overcome all implications of hydrogen usage, providing better and more reliable results. A practical method translation to detect EO (ethylene oxide) and 1,4-dioxane was developed by Indorama Ventures in Woodlands, showing the performance of the new HydroInert ion source on daily operation. The 5977C GC/MSD equipped with a Pal 3 headspace and Hydroinert source, was able to successfully measure at a limit of quantification (LOQ) of 40ppb without substituting for sensitivity or linearity as compared to a Helium GCMS system.
