Presentation Profile
Finding needles in chemical haystacks: Chemometric workflows to streamline GC×GC-TOF MS data analysis
Currently Scheduled: 10/11/2022 - 9:20 AM - 9:40 AM
Room: Convention Center Walkway
Main Author
Matthew Edwards - SepSolve Analytical
- Laura McGregor - SepSolve Analytical
- Bob Green - SepSolve Analytical
- Kevin Kyle - Schauenburg Analytics
Abstract:
Comprehensive two-dimensional gas chromatography (GCxGC) has been proven to be the ideal platform for the analysis of complex petrochemical samples, especially when coupled with time-of-flight mass spectrometry (TOFMS), as it delivers improved separation and confident compound assignment.
Historically, GCxGC data processing has been perceived as being difficult to use, and extremely time-consuming. However, advances in chemometric software have overcome this challenge to ensure that data processing is no longer the ‘bottleneck’ of analytical workflows.
Here, we demonstrate how tile-based chemometrics can be applied to automatically uncover differences between complex chromatograms, delivering meaningful information across a range of GCxGC applications.
