Presentation Profile
Ten Plus Years of Ionic Liquid Capillary Column Development
Currently Scheduled: 10/16/2019 - 12:30 PM - 1:00 PM
Room: Exhibit Hall Room A4
Main Author
Leonard Sidisky - MilliporeSigma (Supelco)
- James Desorcie - Milliporesigma
- Greg Baney - Milliporesigma
- Kathleen Kiefer - Milliporesigma
Abstract:
Ionic liquid capillary columns were first introduced as commercial products around ten years ago. Over the years there have been numerous studies on these unique combinations of cations and anions that provide insights into the selectivity and stability of these interesting stationary phases. These phases have been demonstrated to provide very unique selectivity’s compared to traditional highly polar polysiloxane or polyethylene glycol based phases. Their selectivity is made possible due to the various combinations of cations and anions that are available along with spacer groups used to prepare these germinal dicationic phases. Columns prepared with di- or tricationic phases and newer phases that contain a PEG or branched chain alkyl linkage chain have the ability to perform many of the same applications as columns made with polysiloxane polymer or polyethylene glycol stationary phases of similar polarity, but with slight elution order changes. Many times this results in increased resolution and/or shorter run times. We are continuing the work on evaluating and developing new ionic liquids stationary phases and new applications with them. This presentation will provide a look back on some of the past developments with ionic liquid stationary phases while also updating current studies.
