Presentation Profile
Systematic Approach for the Optimization of on-line Supercritical Fluid Extraction – Supercritical Fluid Chromatography – Tandem Mass Spectrometry
Currently Scheduled: 1/18/2018 - 9:30 AM - 10:00 AM
Room: Room 381 B
Main Author
Paige Wicker Graduate Research Assistant - The University of Texas at Arlington
Abstract:
On-line supercritical fluid extraction - supercritical fluid chromatography (SFE-SFC) is a relatively new tool in the arsenal of analytical chemistry. For effective operation of the instrument, many extraction and chromatographic variables require consideration. Although these variables are generally understood as they apply to the individual techniques, when the two techniques are coupled online, there is a fundamental lack of understanding of how the variables interact. Our goal is to establish a streamlined work flow for SFE-SFC-MS/MS method development using multivariate experimental design approaches for online sample preparation, analyte separation, detection, and quantification for use in environmental analysis.
